Superparamagnetic CoFe2O4@Au with High Specific Absorption Rate and Intrinsic Loss Power for Magnetic Fluid Hyperthermia Applications

doi:10.1007/s40195-018-0830-5

Abstract

Abstract:

CoFe₂O₄ nanoparticles (NPs) and surface modified with gold (Au) have been synthesized by a thermal decomposition method. The obtained NPs and formation of CoFe₂O₄@Au core-shell (CS) were confirmed by characterizing their structural and optical properties using X-ray powder diffraction (XRD) patterns, Fourier transform infrared spectroscopy, Raman spectroscopy, UV-Visible and photoluminescence studies. Morphological and compositional studies were carried out using high-resolution transmission electron microscopy and energy-dispersive X-ray spectroscopy, while the magnetic properties were determined using alternating gradient magnetometer and Mossbauer to define the magneto-structural effects of shell formation on the core NPs. Induction heating properties of CoFe₂O₄ and CoFe₂O₄@Au CS magnetic nanoparticles (MNPs) have been investigated and correlated with magneto-structural properties. Specific absorption rate and intrinsic loss power were calculated for these MNPs within the human tolerable range of frequency and amplitude, suggesting their potential in magnetic fluid hyperthermia therapy for possible cancer treatment.

Key words: CoFe₂O₄@Au, Superparamagnetic, Specific, absorption, rate, (SAR), Intrinsic, loss, power, (ILP), Magnetic, fluid, hyperthermia

Sandip Sabale, Vidhya Jadhav, Shubhangi Mane-Gavade, Xiao-Ying Yu. Superparamagnetic CoFe₂O₄@Au with High Specific Absorption Rate and Intrinsic Loss Power for Magnetic Fluid Hyperthermia Applications[J]. Acta Metallurgica Sinica (English Letters), 2019, 32(6): 719-725.

Figures/Tables 5

Fig. 1 Structural, optical and magnetic properties of CoFe2O4NPs (red) and CoFe2O4@Au CSs (blue) NPs. X-ray diffraction pattern a (filled blue circles and red square showing the representative peaks for Au and CoFe2O4 in core-shell pattern); infrared absorption spectra b; Raman spectra showing the Raman active bands excited at 488 nm c; room temperature M-H curves d (the inset shows the CoFe2O4@Au CSs suspension before a, after b an external magnetic field)

Table 1 Summary of the crystallite size from XRD (DXRD), TEM diameter (DTEM), saturation magnetization (MS), coercivity (HC), composition from EDS analysis, average isomer shift (IS) and internal hyperfine field (Hf) from Mossbauer analysis of obtained MNPs

Sample	D_XRD (nm)	D_TEM (nm)	M_S (emu g^-1)	H_C (Oe)	Composition (wt%)				I_S (mm s^-1)	H_f (mm s^-1)
Sample	D_XRD (nm)	D_TEM (nm)	M_S (emu g^-1)	H_C (Oe)	O	Fe	Co	Au	I_S (mm s^-1)	H_f (mm s^-1)
CoFe₂O₄	4.8?±?0.83	4.50?±?0.5	42.59	7.65	21.87	50.75	27.37	-	0.373?±?0.041	31.6?±?1.40
CoFe₂O₄@Au	5.9?±?0.35	5.10?±?0.5	33.02	0.0	21.18	41.77	22.74	14.31	0.328?±?0.028	26.6?±?1.10

Fig. 2 Mossbauer spectra recorded at room temperature of CoFe2O4 NPs a and CoFe2O4@Au CSs b, (sphere points showing the recorded data points and the gray area showing the distribution of hyperfine field fit using NORMOS/DIST program); representative HRTEM micrographs of CoFe2O4NPs c, d, CoFe2O4@Au CSs e, f

Fig. 3 Temperature-time curves of a 5 mg mL-1; b 10 mg mL-1 CoFe2O4 MNPs; c 5 mg mL-1; d 10 mg mL-1 CoFe2O4@Au CS at different applied AC magnetic fields (dotted line showing the threshold hyperthermia temperature at respective time in s)

Table 2 Calculated rise in temperature (ΔT, °C), specific absorption rate (SAR, W g-1) and intrinsic loss power (ILP, nHm2 kg-1) of CoFe2O4 NPs and CoFe2O4@Au CSs NPs

Applied field (H)?→?		13.3 (kA m^-1)			20.0 (kA m^-1)			26.7 (kA m^-1)
Sample	Conc. (mg mL)	ΔT	SAR	ILP	ΔT	SAR	ILP	ΔT	SAR	ILP
CoFe₂O₄	5	12.16	32.81	0.67	20.88	54.26	0.49	25.89	68.85	0.35
CoFe₂O₄	10	14.83	17.89	0.37	26.65	38.82	0.35	35.43	53.76	0.27
CoFe₂O₄@Au	5	14.88	33.38	0.68	20.08	40.32	0.37	27.94	54.97	0.28
CoFe₂O₄@Au	10	21.00	16.91	0.35	26.47	21.21	0.19	31.10	26.64	0.14

References

[1]	H. Shokrollahi, J. Magn. Mag. Mater. 426, 74(2017)
[2]	S.M. Silva, R. Tavallaie, L. Sandiford, R.D. Tilley, J.J. Gooding, Chem. Commun. 52(48), 7528(2016)
[3]	S. Sabale, P. Kandesar, V. Jadhav, R. Komorek, R.K. Motkuri, X.Y. Yu, Biomater. Sci. 5(11), 2212(2017)
[4]	J.C. Li, Y. Hu, J. Yang, P. Wei, W.J. Sun, M.W. Shen, G.X. Zhang, X.Y. Shi, Biomaterials 38, 10 (2015)
[5]	W. Gao, L.F. Ji, L. Li, G.W. Cui, K.H. Xu, P. Li, B. Tang, Biomaterials 33(14), 3710 (2012)
[6]	J.H. Lee, J.T. Jang, J.S. Choi, S.H. Moon, S.H. Noh, J.W. Kim, J.G. Kim, I.S. Kim, K.I. Park, J. Cheon, Nat. Nano. 6(7), 418(2011)
[7]	S. Sabale, V. Jadhav, V. Khot, X. Zhu, M. Xin, H. Chen, J. Mater. Sci. Mater. Med. 26(3), 127(2015)
[8]	S. Sabale, V. Khot, V. Jadhav, X.L. Zhu, Y.H. Xu, Acta Metall. Sin. (Engl. Lett.) 27(6), 1122(2014)
[9]	N.R. Panda, D. Sahu, B.S. Acharya, P. Nayak, S.P. Patil, D. Das, Acta Metall. Sin. (Engl. Lett.) 27(4), 563(2014)
[10]	Y. Pineiro, Z. Vargas, J. Rivas, M.A. Lopez-Quintela, Eur. J. Inorg.Chem. 27, 4495(2015)
[11]	N. Bachan, A. Asha, W. Jothi Jeyarani, D. Arun Kumar, J. Merline Shyla, Acta Metall. Sin. (Engl. Lett.) 28(11), 1317(2015)
[12]	V. Revathi, S. Dinesh Kumar, P. Chithra Lekha, V. Subramanian, T.S. Natarajan, C. Muthamizhchelvan, Acta Metall. Sin. (Engl. Lett.)27(4), 557 (2014)
[13]	H.Y. Zhao, L. Liu, J. He, C.C. Pan, H. Li, Z.Y. Zhou, Y. Ding, D. Huo, Y. Hu, Biomaterials 51, 194 (2015)
[14]	I. Robinson, L.D. Tung, S. Maenosono, C. Walti, N.T.K. Thanh, Nanoscale 2(12), 2624 (2010)
[15]	Y.M. Shao, L.C. Zhou, C. Bao, Q. Wu, W.L. Wu, M.Z. Liu, New J.Chem. 40(11), 9684(2016)
[16]	Q.D. Xia, S.S. Fu, G.J. Ren, F. Chai, J.J. Jiang, F.Y. Qu, New J.Chem. 40(1), 818(2016)
[17]	A. Mikalauskaite, R. Kondrotas, G. Niaura, A. Jagminas, J. Phys. Chem. C 119(30), 17398 (2015)
[18]	G.V.M. Jacintho, A.G. Brolo, P. Corio, P.A.Z. Suarez, J.C. Rubim, J. Phys. Chem. C 113(18), 7684 (2009)
[19]	G. Shemer, E. Tirosh, T. Livneh, G. Markovich, J. Phys. Chem. C 111(39), 14334 (2007)
[20]	M. Abdulla-Al-Mamun, Y. Kusumoto, T. Zannat, Y. Horie, H. Manaka, RSC Adv. 3(21), 7816(2013)
[21]	C.X. Zhang, Q. Luo, J.H. Shi, L.Y. Yue, Z.B. Wang, X.H. Chen, S.M. Huang, Nanoscale 9(8), 2852 (2017)
[22]	P.L. Andrade, V.A.J. Silva, J.C. Maciel, M.M. Santillan, N.O. Moreno, L.D. Valladares, A. Bustamante, S.M.B. Pereira, M.P.C. Silva, J.A. Aguiar, Hyperfine Interact. 224(1-3), 217(2014)
[23]	S. Karamipour, M.S. Sadjadi, N. Farhadyar, Spectrochim. Acta A Mol. Biomol. Spectrosc. 148, 146(2015)
[24]	R.R. Wildeboer, P. Southern, Q.A. Pankhurst, J. Phys. D Appl. Phys. (2014).

Superparamagnetic CoFe₂O₄@Au with High Specific Absorption Rate and Intrinsic Loss Power for Magnetic Fluid Hyperthermia Applications

RichHTML

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

Figures/Tables 5

References

Related Articles 15

Recommended Articles

Metrics

Comments

[1]	Baojie Wang, Daokui Xu, Tianyu Zhao, Liyuan Sheng. Effect of CaCl₂ and NaHCO₃ in Physiological Saline Solution on the Corrosion Behavior of an As-Extruded Mg-Zn-Y-Nd alloy [J]. Acta Metallurgica Sinica (English Letters), 2021, 34(2): 239-247.
[2]	Meng Yan, Cong Wang, Tianjiao Luo, Yingju Li, Xiaohui Feng, Qiuyan Huang, Yuansheng Yang. Effect of Pulsed Magnetic Field on the Residual Stress of Rolled Magnium Alloy AZ31 Sheet [J]. Acta Metallurgica Sinica (English Letters), 2021, 34(1): 45-53.
[3]	Tao Liu, Yuejiao Chen, Libao Chen. 3D Printing Engineered Multi-porous Cu Microelectrodes with In Situ Electro-Oxidation Growth of CuO Nanosheets for Long Cycle, High Capacity and Large Rate Supercapacitors [J]. Acta Metallurgica Sinica (English Letters), 2021, 34(1): 85-97.
[4]	Xudong Du, Feng Wang, Zhi Wang, Xingxing Li, Zheng Liu, Pingli Mao. Hot Tearing Susceptibility of AXJ530 Alloy Under Low-Frequency Alternating Magnetic Field [J]. Acta Metallurgica Sinica (English Letters), 2020, 33(9): 1259-1270.
[5]	Jia-Qi Zhao, Hua Tian, Zhong Wang, Xue-Jiao Wang, Jun-Wei Qiao. FCC-to-HCP Phase Transformation in CoCrNi_x Medium-Entropy Alloys [J]. Acta Metallurgica Sinica (English Letters), 2020, 33(8): 1151-1158.
[6]	Chengbo Yang, Jing Zhang, Meng Li, Xuejian Liu. Soft-Magnetic High-Entropy AlCoFeMnNi Alloys with Dual-Phase Microstructures Induced by Annealing [J]. Acta Metallurgica Sinica (English Letters), 2020, 33(8): 1124-1134.
[7]	Shikai Wu, Wei Gao, Tao Lu, Ye Pan. Co-Free High-Entropy Alloys Powders Immobilized by Electrospray and Microfluidics for Decolorization of Azo Dye [J]. Acta Metallurgica Sinica (English Letters), 2020, 33(8): 1103-1110.
[8]	Lujun Zhou, Shanwu Yang, Yi Dong, Wenhua Zhang, Jianwen Ding, Guoliang Liu, Chengjia Shang, Raja Devesh Kumar Misra. Characterization of Compactness of Rust Layers on Weathering Steels by an Adsorption/Dehydration Test of Ethanol [J]. Acta Metallurgica Sinica (English Letters), 2020, 33(6): 846-856.
[9]	Ming He, Xian-Liang Li, Qing-Wei Wang, Qiang Wang, Zhi-Yuan Liu, Chong-Jun Wang. Influence Factors Analysis of Fe-C Alloy Blocking Layer in the Electromagnetic Induction-Controlled Automated Steel Teeming Technology [J]. Acta Metallurgica Sinica (English Letters), 2020, 33(5): 671-678.
[10]	Jiahao Wang, Lin Xu, Ruizhi Wu, Jing Feng, Jinghuai Zhang, Legan Hou, Milin Zhang. Enhanced Electromagnetic Interference Shielding in a Duplex-Phase Mg-9Li-3Al-1Zn Alloy Processed by Accumulative Roll Bonding [J]. Acta Metallurgica Sinica (English Letters), 2020, 33(4): 490-499.
[11]	Fu-Yue Wang, Xiang-Jie Wang, Wei Sun, Fang Yu, Jian-Zhong Cui. Low Frequency Electromagnetic Casting of 2195 Aluminum-Lithium Alloy and Its Effects on Microstructure and Mechanical Properties [J]. Acta Metallurgica Sinica (English Letters), 2020, 33(3): 338-350.
[12]	Bing Li, Bugang Teng, Baoting Zhang. Integrated Extrusion-Shear Forming Process of the Solid-State Recycled AZ80 Magnesium Alloy via Hot Press Sintering [J]. Acta Metallurgica Sinica (English Letters), 2020, 33(3): 351-361.
[13]	Hao-Yi Niu, Fang-Fang Cao, Kun-Kun Deng, Kai-Bo Nie, Jin-Wen Kang, Hong-Wei Wang. Microstructure and Corrosion Behavior of the As-Extruded Mg-4Zn-2Gd-0.5Ca Alloy [J]. Acta Metallurgica Sinica (English Letters), 2020, 33(3): 362-374.
[14]	Le Zhang, Wei Wang, fei Xiao, Shahzad M. Babar, Yiyin Shan, Ke Yang. Ultra-thin Laminated Metal Composites with Ultra-high Strength and Excellent Soft Magnetic Properties [J]. Acta Metallurgica Sinica (English Letters), 2020, 33(3): 385-390.
[15]	Yan Dai, Xian-Hua Chen, Tao Yan, Ai-Tao Tang, Di Zhao, Zhu Luo, Chun-Quan Liu, Ren-Ju Cheng, Fu-Sheng Pan. Improved Corrosion Resistance in AZ61 Magnesium Alloys Induced by Impurity Reduction [J]. Acta Metallurgica Sinica (English Letters), 2020, 33(2): 225-232.